This is an older question, and in the meantime there has been a lot of development done on the DataStax Python driver. This is probably the best choice today because it's the most active and up to date (with support for CQL3, for example, as you mentioned).
The Pycassa author is also recommending a switch:
pycassa does not support CQL or Cassandra's native protocol, which are a replacement for the Thrift interface that pycassa is based on. If you are starting a new project, it is highly recommended that you use the newer DataStax python driver instead of pycassa.