These DB calls refer to the new Migration HIstory Table feature included in EF6 when using Code-First:
Migrations history table is a table used by Code First Migrations to store details about migrations applied to the database. By default the name of the table in the database is __MigrationHistory and it is created when applying the first migration do the database. In Entity Framework 5 this table was a system table if the application used Microsoft Sql Server database. This has changed in Entity Framework 6 however and the migrations history table is no longer marked a system table.
If you aren't using them, these calls shouldn't cause any harm. You can always disable them or have EF create DB change scripts for you instead.