I figured it out:
people = [("John","Smith"), ("Jane","Doe"), ("Jane","Smith")]
table_data = []
for i, person in enumerate(people):
# Add a row to the table
table_data.append([person[0], person[1]])
# Create the table
issue_table = Table(table_data, colWidths=[doc.width/3.0]*3)
Story.append(issue_table)