No, not on modern hardware. Modern hardware can perform all normal double precision multiplications/additions/subtractions in one or two cycles. Possible exceptions to this are denormalized numbers and special values like +/-zero, +/-infinity, and NANs. These exceptions take longer if there is a difference.
However, as with all performance related questions, truth is only in measurements. If this is important to you, measure it, then you know what to do.