No.
ZODB is somewhat misnamed. It's not a "database" like Postgres or MySQL is a database that has constraints and a query language and all that stuff that people presume a database has. It's, instead, a persistent object store. There's nothing that ZODB does for you that Python's pickle module doesn't do for you except manage working sets that are larger than available memory, handle transactions, and allow you to share object representations between processes. It's in effect "superpickle".
So your answer wouldn't be any different than if you had asked the same question about pickle, really.