For truly high performance, mutability is required, in one specific case : Provided that your code is perfectly optimized and that you master everything it is doing down to the cache (L1, L2) pattern of access of your program, then nothing beats a low level, to the metal approach.
This happens mostly only when you have one well specified problem that stays constant for 20 years, aka mostly in scientific tasks.
As soon as you depart from this specific case, in 99.99% the bottlenecks arise from having a too low level representation (induced by a low level langage) in which you can't express the final, real-world optimization trade-off of your problem at hand.
Bottom line, for performance, the following approach is the only way (i think) :
- High level / algorithmic optimization first
- Once every high level ways has been explored, low level optimization
You can see how as a consequence of that :
You should never optimize anything without FIRST measuring the impact : improvements should only be made if they yield enormous performance gains and/or do not degrade your domain logic.
You eventually will reach, if your problem is stable and well defined, the point where you will have no choice but to go to the low level, and play with memory/mutability