The OPTIONS request is coming from your browser, not PouchDB. From WikiPedia:
the specification mandates that browsers “preflight” the request, soliciting supported methods from the server with an HTTP OPTIONS request header
The error you're seeing isn't fatal, usually. Check your local database to see if replication actually failed. If you are only seeing the error from the OPTIONS request, then it's possible replication went without a problem.
Also make sure you are using the latest CouchDB (1.3.x I beleive) as it has built-in CORS support.