It is automatable as they provide an API.
API Reference - Amazon Elastic Transcoder : http://docs.aws.amazon.com/elastictranscoder/latest/developerguide/api-reference.html
You should be able to call the APIs from anywhere, even from your Django app.
This example helps you setup a video trans-coding pipeline. http://docs.aws.amazon.com/elastictranscoder/latest/developerguide/getting-started.html