No, you can't do this. You'll find that your application throws an exception if you try:
The lifetime manager is already registered. Lifetime managers cannot be reused, please create a new one.
Description: An unhandled exception occurred during the execution of the current web request. Please review the stack trace for more information about the error and where it originated in the code.
Exception Details: System.InvalidOperationException: The lifetime manager is already registered. Lifetime managers cannot be reused, please create a new one.