I found the answer. Create webpage with two frames
<html>
<frameset rows=20%,80%>
<frame src="frame1.html" name="myFrame1" />
<frame src="frame2.html" name="myFrame2" />
</frameset>
</html>
and place a link in frame1.html with target set to myFrame2
<a id="link" href="frame3.html" target="myFrame2">Click me!</a>