Can I apply check out rules to a single document in a document library and not the whole library?

Question

Is it possible to apply check in/out rules to a single document in a document library without applying the same rules across the document library via the Library "Version Settings" section?

Answer 1

No, that is a library level setting.

SPFile.RequiresCheckout is a read only property that tells you is 'check out required' setting set for the document library.