Solved by following steps:
- delete subsites
- deactivated MU as described here http://wpengineer.com/2056/remove-wordpress-multisite-feature-todo-list/
- the most important: changed base domain and home from mydomain.local to www.mydomain.local (from database table "wp_options", edit siteurl & home fields)
- deactivated all plugins
- enable MU
- reactivated all plugins
that's all!