Thunderbird and other programs from Mozilla don't use win32com
. Instead, they use xpcom
. See [http://kb.mozillazine.org/Calling_Thunderbird_from_other_programs.
There is a python module, PyXPCOM, which could help you out with controlling Mozilla from Python, if you really want to.
You can also use AutoHotKey to script Thunderbird and many other programs, too.