Each control-change event is an independent event, so it needs its own delta time, its own status byte, and its own parameter byte(s). (The status byte can be omitted if it has the same value as the previous one, but this depends only on the status byte's value, and not on whether the events are actually related.)
What happens if you send the MSB message without the LSB message is not clearly specified, and even if it were, you could not be sure that devices would implement it correctly.
To be safe, to change a control with a 14-bit value, send both the MSB and LSB messages, in that order.