Javascript doesn't have any biginteger type, so you would need to use an array to hold that much information.
An array of 0 and 1 values would make it easy to implement functions for it, but not very efficient.
A regular number in Javascript is a double precision floating point number, so it can hold 52 bits of numeric information (ref), but you would use slightly less to be far away from any rounding errors, for example 48 bits.
The bitwise operators in Javascript work with 32 bit integers, i.e. a double is converted to a 32 bit integer when used with a bitwise operator. If you want to use the bitwise operators on the data, you could choose to store 32 bits per item in the array.