i think what you're asking for is called "multiple sites". it appears in the table at https://www.djangopackages.com/grids/g/blogs/ and for mezzanine is described at http://mezzanine.readthedocs.org/en/latest/deployment.html#multiple-sites-and-multi-tenancy . similarly, for django-cms it is described at https://groups.google.com/forum/#!topic/django-cms/jQNWVos9vg8
both of these seem to be built on the django sites framework - https://docs.djangoproject.com/en/dev/ref/contrib/sites/
this all just from googling - i have no experience on this. i am answering because i suspect your question will be closed soon, as s.o. editors don't like questions that ask people (or could be interpreted as asking) to recommend things. so better half an answer now, than none later...