set("paths", ...)
returns a Promise, so, your problem can be solved in the following way:
//select node
_Tree.set("path", ["root", "folder49", "file25_folder49"]).then(
function(path) {
// executes when set("path", ..) is complete
var item = _Tree.model.store.data[2526];
_Tree.onClick(item);
}
);