you have to restart php-fpm service :
service php-fpm restart
service php5-fpm restart //if you avec php5
or
/etc/init.d/php-fpm restart
/etc/init.d/php5-fpm restart //if you avec php5
EDIT :
you have php-fastcgi, so replace ftpm by fastcgi :
/etc/init.d/php-fastcgi restart