Not entirely sure which bit you need help with; getting the drop downs to work or the formula to go in cell B15 (or both). I'll answer both and hopefully we can get you where you need to be.
Getting the drop downs to work I think you may have sorted but just in case:
- Select cell B10, click Data --> Data Valication
- In the popup select
- List from the Allow dropdown In Source you can click the icon and
select the cells
=$B$1:$E$1
- Click the little icon again and then OK and you're good to go.
Repeat for the other drop downs. Note, if your list is on a different worksheet you need to use a named range to reference it.
As for picking up the correct rate for cell B15 this should work:
=VLOOKUP(B11,$A$2:$G$6,MATCH($B$10,$A$1:$G$1,0),0)