Image movement calibration

Question

I have a series of mostly identical images taken over a period of time. However, the objects in the images drifts over time, and I would like to correct for this. What is a good was to do this?

[EDIT] Okay, I may have to explain why I'm going this. I've taken some series of X-ray images of objects at different X-ray energies. I now want to compare the object are the various energies, but since it drifts I have to correct for the drift first. The object has no sharps edges or anything which otherwise would be easy to use for alignment. Therefore I'm looking for a more general method

Answer 1

In its general form this problem is known as image registration, and is a large topic of research in the image processing community. There are a varity of different methods and algorithms, often specialized for image modality. Depending on your images, to do this could be easy, or it could be difficult. I would recommend using one of the registration methods found in the file-exchange.

Based on your description of your images, it seems a rigid transformation should be enough. In that case, this method should work nicely.