You are using massively too many concurrent connections. PostgreSQL will be wasting lots of its time on housekeeping and juggling concurrent queries. All the concurrent work will be fighting for CPU and buffer space, there'll be heavy contention on spinlocks, and it'll all generally be a mess.
On an 8 core machine, you should probably not have more than 20 actively working connections if you're mostly CPU constrained. If you're I/O limited, you can go higher, but 350 is just ridiculous.
If possible, put a PgBouncer in transaction pooling mode in front of your PostgreSQL instance, so queries get queued up and executed rapidly in series instead of slowly in parallel.
See number of database connections (Pg wiki).
Additionally, PostGIS can be very CPU-heavy. It sometimes needs to do very complex calculations. I suggest using the auto_explain
module to record long running queries, and using pg_stat_statements
/ pg_stat_plans
to record what's taking up resources. Examine these queries to see if they need improvement.
Your idle in transaction
sessions must be dealt with, too. Depending on why they're idle and whether they have a transaction ID or not, they might be causing serious table bloat. They're also creating unnecessary signalling overhead within PostgreSQL, as it has to do more co-ordination with backends that're actively doing things. Finally, the number of open transactions its self increases the cost of some internal housekeeping operations.
So. Your DB will probably perform better if you reduce the connection counts, put a PgBouncer in transaction pooling mode in front, and fix those idle connections.