For layout purposes, dpi doesn't matter. Position something 10pts away from the edge and it will be about 10pts away from the edge regardless of dpi. When showing text and images, the OS will show at the best resolution it can.
That's why two forms of the image should be stored with the app. MyImage.png and MyImage@2x.png. The @2x image is just that, an image that is double in size that will be shown in the same position and size as the original, just at a better resolution.