Just in case anyone ends up here for same reason I did.
Was going crazy because onload and onerror were not firing in the page I was building. Tried copy pasting
var myimage = new Image();
myimage.onload = function() { alert("Success"); };
myimage.onerror = function() { alert("Fail"); };
myimage.src = "mog.gif" //Doesn't exist.
Which was working within codepen and random otherwise blank pages.
Turns out the problem I was having was that I was doing AJAX requests earlier in the page. This involved authorization which in turn involved a call to
setRequestHeader();
This was resulting in a net::ERR_FILE_NOT_FOUND error instead of the expected GET mog.gif 404 (Not Found)
This seemed to prevent proper triggering of events.
Revert with
xhr.setRequestHeader("Authorization", "");