Its probably not worth the trouble.
An attacker just needs a handle to the process, and if you rename the exe you just make it a tiny bit more difficult, but not that much. For example simply monitoring the processes that open the firefox history database or any process that does a DNS lookup for the firefox update server would be good enough for that. Or just MD5 summing all the exes and having a set of known binary images.
Basically if you have some code that can inject DLLs or code into foreign processes you have already lost control of the system.