You CAN specify absolute paths in iOS, but the path in your example is probably used in Mac OS, which is laid out a little differently. You can specify paths to fopen() as you say, but there is more work to finding out what the first part of that path really is.
The iOS puts all AppStore apps into folders with randomly generated sandbox directory names. It is basically the the hexadecimal string of a GUID. So you need to use methods from iOS frameworks to get the first part of the path (or URL) to your file.
If the file is part of the app bundle so it can ship with the app, then you will need to use NSBundle methods to find the path to the file.
If the file is generated or downloaded after the app starts up on the device, then you need to use NSFileManager methods to determine the path to the directory of the file. (Typically the Documents directory. You can build a directory structure of your choice within the sandbox.)