There are different ways you can configure LEFT JOIN when you have 4 tables.
Query 1
In the question you have (more or less):
SELECT t1.col, t2.info2, t3.info3, t4.info4
FROM table1 t1
LEFT JOIN table2 t2 ON t1.col = t2.col
LEFT JOIN table3 t3 ON t1.col = t3.col
LEFT JOIN table4 t4 ON t1.col = t4.col
WHERE ...
Note that I've made sure that each table is needed by selecting a value from each table. If there was no column selected from Table4, for example, then the query optimizer would probably spot that and deduce that it does not need to even look at Table4.
The query is a bit like a snowflake; Table1 is (left) joined in turn Table2, Table3 and Table4. All the rows in Table1 that match the criteria in the WHERE clause will appear in the output (at least once). If there are any rows in Table2 that match the ON t1.col = t2.col
condition, they will be selected; if there are no such rows, a row of NULLs will be used instead. Suppose that there are 2 rows in Table2 that match R1 from Table1, and 3 rows in Table3 that match R1 from Table1, and 4 rows in Table4 that match R1. Then there will be 24 rows in the output for R1 (unless the WHERE clause eliminates some of those).
Query 2
SELECT t1.col, t2.info2, t3.info3, t4.info4
FROM table1 t1
LEFT JOIN table2 t2 ON t1.col = t2.col
LEFT JOIN table3 t3 ON t2.col = t3.col
LEFT JOIN table4 t4 ON t3.col = t4.col
WHERE ...
This is a different query altogether. It is a long chain: Table1 is joined to Table2; Table2 is joined to Table3; and Table3 is joined to Table4.
Clearly, you can have other ways of joining the tables too if you wish.
Sample data
Consider this data. The syntax is correct for Informix, but if the TEMP notation for creating a temporary table doesn't work for your DBMS, drop the keyword TEMP and it should be OK.
CREATE TEMP TABLE table1 (col CHAR(2) NOT NULL PRIMARY KEY, info1 CHAR(15) NOT NULL);
INSERT INTO table1 VALUES('R1', 'Info T1 R1');
INSERT INTO table1 VALUES('R2', 'Info T1 R2');
INSERT INTO table1 VALUES('R3', 'Info T1 R3');
INSERT INTO table1 VALUES('R4', 'Info T1 R4');
INSERT INTO table1 VALUES('R5', 'Info T1 R5');
INSERT INTO table1 VALUES('R6', 'Info T1 R6');
INSERT INTO table1 VALUES('R7', 'Info T1 R7');
INSERT INTO table1 VALUES('R8', 'Info T1 R8');
CREATE TEMP TABLE table2 (col CHAR(2) NOT NULL, info2 CHAR(15) NOT NULL, sub2 INTEGER, PRIMARY KEY(col, sub2));
INSERT INTO table2 VALUES('R1', 'Info T2 R1 V1', 1);
INSERT INTO table2 VALUES('R1', 'Info T2 R1 V2', 2);
INSERT INTO table2 VALUES('R2', 'Info T2 R2 V1', 1);
INSERT INTO table2 VALUES('R5', 'Info T2 R5 V1', 1);
INSERT INTO table2 VALUES('R6', 'Info T2 R6 V1', 1);
INSERT INTO table2 VALUES('R7', 'Info T2 R7 V1', 1);
CREATE TEMP TABLE table3 (col CHAR(2) NOT NULL, info3 CHAR(15) NOT NULL, sub3 INTEGER, PRIMARY KEY(col, sub3));
INSERT INTO table3 VALUES('R1', 'Info T3 R1 V1', 11);
INSERT INTO table3 VALUES('R1', 'Info T3 R1 V2', 12);
INSERT INTO table3 VALUES('R1', 'Info T3 R1 V3', 13);
INSERT INTO table3 VALUES('R3', 'Info T3 R3 V1', 11);
INSERT INTO table3 VALUES('R5', 'Info T3 R5 V1', 11);
INSERT INTO table3 VALUES('R6', 'Info T3 R6 V1', 11);
CREATE TEMP TABLE table4 (col CHAR(2) NOT NULL, info4 CHAR(15) NOT NULL, sub4 INTEGER, PRIMARY KEY(col, sub4));
INSERT INTO table4 VALUES('R1', 'Info T4 R1 V1', 21);
INSERT INTO table4 VALUES('R1', 'Info T4 R1 V2', 22);
INSERT INTO table4 VALUES('R1', 'Info T4 R1 V3', 23);
INSERT INTO table4 VALUES('R1', 'Info T4 R1 V4', 24);
INSERT INTO table4 VALUES('R4', 'Info T4 R4 V1', 21);
INSERT INTO table4 VALUES('R5', 'Info T4 R5 V1', 21);
INSERT INTO table4 VALUES('R5', 'Info T4 R5 V2', 22);
The output from the two queries is different. The WHERE clause was omitted altogether.
Output from Query 1
R1 Info T2 R1 V1 Info T3 R1 V1 Info T4 R1 V1
R1 Info T2 R1 V1 Info T3 R1 V1 Info T4 R1 V2
R1 Info T2 R1 V1 Info T3 R1 V1 Info T4 R1 V3
R1 Info T2 R1 V1 Info T3 R1 V1 Info T4 R1 V4
R1 Info T2 R1 V2 Info T3 R1 V1 Info T4 R1 V1
R1 Info T2 R1 V2 Info T3 R1 V1 Info T4 R1 V2
R1 Info T2 R1 V2 Info T3 R1 V1 Info T4 R1 V3
R1 Info T2 R1 V2 Info T3 R1 V1 Info T4 R1 V4
R1 Info T2 R1 V1 Info T3 R1 V2 Info T4 R1 V1
R1 Info T2 R1 V1 Info T3 R1 V2 Info T4 R1 V2
R1 Info T2 R1 V1 Info T3 R1 V2 Info T4 R1 V3
R1 Info T2 R1 V1 Info T3 R1 V2 Info T4 R1 V4
R1 Info T2 R1 V2 Info T3 R1 V2 Info T4 R1 V1
R1 Info T2 R1 V2 Info T3 R1 V2 Info T4 R1 V2
R1 Info T2 R1 V2 Info T3 R1 V2 Info T4 R1 V3
R1 Info T2 R1 V2 Info T3 R1 V2 Info T4 R1 V4
R1 Info T2 R1 V1 Info T3 R1 V3 Info T4 R1 V1
R1 Info T2 R1 V1 Info T3 R1 V3 Info T4 R1 V2
R1 Info T2 R1 V1 Info T3 R1 V3 Info T4 R1 V3
R1 Info T2 R1 V1 Info T3 R1 V3 Info T4 R1 V4
R1 Info T2 R1 V2 Info T3 R1 V3 Info T4 R1 V1
R1 Info T2 R1 V2 Info T3 R1 V3 Info T4 R1 V2
R1 Info T2 R1 V2 Info T3 R1 V3 Info T4 R1 V3
R1 Info T2 R1 V2 Info T3 R1 V3 Info T4 R1 V4
R2 Info T2 R2 V1
R3 Info T3 R3 V1
R4 Info T4 R4 V1
R5 Info T2 R5 V1 Info T3 R5 V1 Info T4 R5 V1
R5 Info T2 R5 V1 Info T3 R5 V1 Info T4 R5 V2
R6 Info T2 R6 V1 Info T3 R6 V1
R7 Info T2 R7 V1
R8
Output from Query 2
R1 Info T2 R1 V1 Info T3 R1 V1 Info T4 R1 V1
R1 Info T2 R1 V1 Info T3 R1 V1 Info T4 R1 V2
R1 Info T2 R1 V1 Info T3 R1 V1 Info T4 R1 V3
R1 Info T2 R1 V1 Info T3 R1 V1 Info T4 R1 V4
R1 Info T2 R1 V1 Info T3 R1 V2 Info T4 R1 V1
R1 Info T2 R1 V1 Info T3 R1 V2 Info T4 R1 V2
R1 Info T2 R1 V1 Info T3 R1 V2 Info T4 R1 V3
R1 Info T2 R1 V1 Info T3 R1 V2 Info T4 R1 V4
R1 Info T2 R1 V1 Info T3 R1 V3 Info T4 R1 V1
R1 Info T2 R1 V1 Info T3 R1 V3 Info T4 R1 V2
R1 Info T2 R1 V1 Info T3 R1 V3 Info T4 R1 V3
R1 Info T2 R1 V1 Info T3 R1 V3 Info T4 R1 V4
R1 Info T2 R1 V2 Info T3 R1 V1 Info T4 R1 V1
R1 Info T2 R1 V2 Info T3 R1 V1 Info T4 R1 V2
R1 Info T2 R1 V2 Info T3 R1 V1 Info T4 R1 V3
R1 Info T2 R1 V2 Info T3 R1 V1 Info T4 R1 V4
R1 Info T2 R1 V2 Info T3 R1 V2 Info T4 R1 V1
R1 Info T2 R1 V2 Info T3 R1 V2 Info T4 R1 V2
R1 Info T2 R1 V2 Info T3 R1 V2 Info T4 R1 V3
R1 Info T2 R1 V2 Info T3 R1 V2 Info T4 R1 V4
R1 Info T2 R1 V2 Info T3 R1 V3 Info T4 R1 V1
R1 Info T2 R1 V2 Info T3 R1 V3 Info T4 R1 V2
R1 Info T2 R1 V2 Info T3 R1 V3 Info T4 R1 V3
R1 Info T2 R1 V2 Info T3 R1 V3 Info T4 R1 V4
R2 Info T2 R2 V1
R3
R4
R5 Info T2 R5 V1 Info T3 R5 V1 Info T4 R5 V1
R5 Info T2 R5 V1 Info T3 R5 V1 Info T4 R5 V2
R6 Info T2 R6 V1 Info T3 R6 V1
R7 Info T2 R7 V1
R8