Here is an example using a couple of the options:
entity_managers:
games:
connection: games
mappings:
CeradGameBundle:
type: yml
dir: Resources/config/doctrine2
prefix: Cerad\Bundle\GameBundle\Doctrine\Entity
The dir points to where the orm.yml files live. As shown it is relative to the bundle. But you can replace it with an absolute path if you want.
The prefix is basically the namespace of your entities.
As far as multiple prefixes go, you can have multiple mappings for a given manager. Make one mapping per prefix.