There exists an exact algorithm that solves this problem! It is called time-dependent Dijkstra (TDD) and runs about as fast as Dijkstra itself.
Unfortunately, as far as I know, neither igraph nor NetworkX have implemented this algorithm so you will have to do some coding yourself.
Luckily, you can implement it yourself! You need to adapt Dijkstra in single place.
In normal Dijkstra you assign the weight as follows:
With dist
your current distance matrix, u
the node you are considering and v
its neighbor.
alt = dist[u] + travel_time(u, v)
In time-dependent Dijkstra we get the following:
current_time = start_time + dist[u]
cost = weight(u, v, current_time)
alt = dist[u] + cost
TDD Dijkstra was described by Stuart E. Dreyfus. An appraisal of some shortest-path algorithms. Operations Research, 17(3):395–412, 1969
Currently, much faster heuristics are already in use. They can be found with the search term: 'Time dependent routing'.