I really recommend you to use PANDAS to cope with this kind of problem.
for proof that can be simply done with pandas:
import pandas as pd #install this, and read de docs
from StringIO import StringIO #You dont need this
#simulating a reading the file
first_file = """contig17 GRMZM2G052619_P03 x
contig33 AT2G41790.1 x
contig98 GRMZM5G888620_P01 x
contig102 GRMZM5G886789_P02 x
contig123 AT3G57470.1 x"""
#simulating reading the second file
second_file = """y GRMZM2G052619_P03 y
y GRMZM5G888620_P01 y
y GRMZM5G886789_P02 y"""
#here is how you open the files. Instead using StringIO
#you will simply the file path. Give the correct separator
#sep="\t" (for tabular data). Here im using a space.
#In name, put some relevant names for your columns
f_df = pd.read_table(StringIO(first_file),
header=None,
sep=" ",
names=['a', 'b', 'c'])
s_df = pd.read_table(StringIO(second_file),
header=None,
sep=" ",
names=['d', 'e', 'f'])
#this is the hard bit. Here I am using a bit of my experience with pandas
#Basicly it select the rows in the second data frame, which "isin"
#in the second columns for each data frames.
my_df = s_df[s_df.e.isin(f_df.b)]
Output: Out[180]:
d e f
0 y GRMZM2G052619_P03 y
1 y GRMZM5G888620_P01 y
2 y GRMZM5G886789_P02 y
#you can save this with:
my_df.to_csv("result.txt", sep="\t")
chers!