It was as simple as adding "\n" at the end of a line :
'line1 \n line2 \n line3"
ax.annotate('line1 \n line2', xy=(timeNow, y), xycoords='data',
xytext=(-50, 30), textcoords='offset points',
arrowprops=dict(arrowstyle="->"),
verticalalignment='center',
horizontalalignment='center'
)