Assuming you've arranged your tiles where the leftmost column and topmost row are zero:
var column = parseInt(mouseX / tileWidth);
var row = parseInt(mouseY / tileHeight);
BTW, if you eventually move your canvas off the top-left of the page then you must adjust your mouse coordinates by the canvas offset.
Here's an example of how to calculate mouse position:
// references to the canvas element and its context
var canvas=document.getElementById("canvas");
var ctx=canvas.getContext("2d");
// get the offset position of the canvas on the web page
var BB=canvas.getBoundingClientRect();
var offsetX=BB.left;
var offsetY=BB.top;
// listen for mousedown events
canvas.onmousedown=handleMousedown;
function handleMousedown(e){
// tell the browser we will handle this event
e.preventDefault();
e.stopPropagation();
// calculate the mouse position
var mouseX=e.clientX-offsetX;
var mouseY=e.clientY-offsetY;
}