How to disable/enable controllers in JMVC?

Question

Imagine you have one page app using Javascript MVC, which should switch between sub-apps and still stay on the same page. You can load additional controllers and views into the page, but to avoid the conflicts between different controllers, you need to enable the current controller and disable others. You can even destroy the controller and add the current sub-app controllers if needed.

Is it possible? if so, how?

Thanks.