Does it use shared memory or some other IPC mechanism? and is that memory used by multiple applications? Thats the test...
It doesn't have to fork, there could be different code bases (separate executables) sharing some resource. For example is there a monitoring application or interface that gets stats from the app as it runs via some IPC mechanism? Note that there may be other better ways of doing that, it's just an example.
Looking at the headers :
http://www.boost.org/doc/libs/1_52_0/boost/interprocess/sync/windows/mutex.hpp
http://www.boost.org/doc/libs/1_52_0/boost/interprocess/sync/posix/mutex.hpp
There is an overhead and replacing it with a local version (If Safe) could gain you some efficiency. I'm not too familiar with the Posix implementation in all honesty however.
As I said above you might use IPC if an external app were using some say shared memory to get stats or communicate - but if that's not the case for you then you can probably replace them.