Probably I've found a solution. It depends of document.xpath, a way to take a map of it is decompress the .docx and read the ./word/document.xml file.
PATH_CELL = 'the path you individuate in document.xml'
docbody = document.xpath('/w:document/w:body'+PATH_CELL,
namespaces=nsprefixes)[0]
print 'Replacing ...',
docbody = replace(docbody,'Welcome','Hello')
I've found this way to run the game. Any else ?