not using sql or using sql is not really the question you're asking, as all none sql databases are not sql :)
You're looking at RDBMS (SQL,ORALCE, etc) which have relationships and normalization and vs noSQL database, and the answer is that it really depends on what you need, there is not one perfect one for Node.js, it's a matter of preference and need.
Document based noSQL (like CouchDB/MonogoDB/Redis) base their speed on tailing the de-normalization of the database to fit your queries. https://github.com/joyent/node/wiki/modules#database
Here are some popular ones: Some popular ones include:
- MongoDB
- Redis
- Couch
- Riak
Again there is no one answer to fit them all however here is an excellent article on this matter: http://slashdot.org/topic/bi/sql-vs-nosql-which-is-better/