It's best to use a canvas library for this such as GooCanvas. Doing it with cairo alone would require you to listen to mouse events on the whole drawing area, and keep track of where the circles were in order to decide which circle the mouse event belongs to - exactly the problem which the canvas library has already solved for you.
If you are having trouble with goocanvasmm documentation, a look at the documentation for GooCanvas' C API combined with knowledge of how the C API translates into C++ will usually suffice. Although the GooCanvasmm documentation seems fairly extensive to me.