Start a ram disk, such as AMD RamDisk. And install it or copy it to there. It should have an option to backup the ramdisk on shutdown.
[AMD Ramdisk][1] http://www.amd.com/us/products/desktop/radeon-memory/Pages/ramdisk-overview.aspx
Alternatively, buy an SSD which will have a great performance increase over your HDD, and doesn't have the downsides of running stuff from ram (ie losing data on power loss, having to backup to hdd at shutdown etc).