Node.js and Socket.io have become quite famous for their use for making Real Time applications. I have used them for a basic real-time analytics app and it turned out to be pretty real time. Mine was a small project so I didn't really do any load testing but there are some nice reads about the scalability of Node.js and Socket.io:
http://weblog.bocoup.com/node-stress-test-analysis/
http://engineering.linkedin.com/nodejs/blazing-fast-nodejs-10-performance-tips-linkedin-mobile