When you invoke webclient calls on Out-Of-Browser mode it suppose that you have already RootVisual Created, because webclient will run on its Dispatcher apparently. If not, you end up with no response from server, and what is strange, even exception is not thrown !!
Anyway, this Post from Jeremy explains details:
http://csharperimage.jeremylikness.com/2010/05/webclient-and-deploymentcatalog-gotchas.html