Calling ax.grid(False)
should suffice. Self contained example, adding that line to this:
from mpl_toolkits.mplot3d import axes3d
import matplotlib.pyplot as plt
import numpy as np
fig = plt.figure()
ax = fig.add_subplot(111, projection='3d')
ax.grid(False)
X, Y, Z = axes3d.get_test_data(0.05)
ax.plot_wireframe(X, Y, Z, rstride=10, cstride=10)
plt.show()