We currently have no support for generic web frameworks... You're right that you'll just want to configure your project to launch the WSGI server. You can do that by right clicking on the project and going to properties and setting your startup script.
An easy way to get started with this would probably to use wsgiref.simple_server. You can then have a simple script which does something like what simple_server does if it's run as a script:
from wsgiref import simple_server
httpd = simple_server.make_server('', 8000, <your wsgi app here>)
sa = httpd.socket.getsockname()
print "Serving HTTP on", sa[0], "port", sa[1], "..."
import webbrowser
webbrowser.open('http://localhost:8000/xyz?abc')
httpd.handle_request() # serve one request, then exit
For our 2.1 release we're looking at adding templates for a number of web frameworks as well as creating a generic web site project type which would probably work for you. If you have a particular framework you're using let us know as it'd help us prioritize which ones we pick.