Before you jump the gun and just make one huge table, you should sit down and think about if having one massive table really is useful in the long run. Normalization can be a wonderful thing, and depending on the size of your input it would be much less of a hassle to structure everything now rather then later.
As far as deciding what to import, toss it into excel or mysql and drop the fields you don't want/need. Mysql will actually build the structure of your table from the csv file, as long as you give it the right delimiter (comma, semicolon, whatever seperates your fields).