Try:
RewriteEngine On
RewriteCond %{QUERY_STRING} (^|&)option=com_toys(&|$)
RewriteCond %{QUERY_STRING} ^(.*)&brand=([^&]+)(.*)$
RewriteRule ^index\.php$ /index.php?%1%3 [L,R=301]
RewriteCond %{QUERY_STRING} (^|&)option=com_toys(&|$)
RewriteCond %{QUERY_STRING} ^(.*)&location=([^&]+)(.*)$
RewriteRule ^index\.php$ /index.php?%1%3 [L,R=301]
in the htaccess file in your document root, preferably above any rules that you already have.