Since you already use multiprocess uWSGI, enable-threads
will not increase performance. It can only save you some RAM, so if you're not short on memory, you should stay away from threads because of GIL.
As for hyper-threading, don't guess it, test it! Performance gain (or loss) totally depends on the app, so try different setups, including processes
. It's unlikely that you get 2x gain from HT, but still it may be significant.