Have you read over the documentation http://laravel.com/docs/eloquent?
Create a new file inside of ../app/models/
../app/models/Profile.php
** note the file matches the classname
inside the model:
class Profile extends Eloquent {
protected $table = 'profile';
}
Then in your controller or route closure access the model via
$profile = Profile::find(1);
or
$profile = App::make('Profile');
$profile->about = 'About the user';
$profile->save();