No, they won't do anything, the dll/exe of managed program is just a stub(stub means template but essential) program that will attempt to call mscoree, which is the .Net runtime executor, also called the shim, because it would attempt to select the version of .net framework(and the native function name is called _CorExeMain), then the shim itself will bootstrap the .Net framework, and launch a clr instance, then start the procession of IL codes inside the PE, besides that it's just some metadata generated by the CIL compiler, such as resource pools(string pool, constant values), function prototypes, inheritance, and generics types.
For more information, take a deep look at this: http://blog.vuscode.com/malovicn/archive/2007/12/25/net-foundations-net-execution-model.aspx , You won't be disappointed.