Thanks for all the help David.
For anyone else who runs into this problem, here's what you need to do.
Right click on the Project name (ConsoleApplication1, ect) and under C/C++ general insure that your additional include directories include youe python include, Lib, and libs folders. As well as the boost root and the boost lib(32/64) folder.
Under the linker menu, in the input sub catagory, for additional dependencies, you'll need to add this into there.
C:\Python33\libs\python33.lib
C:\boost_1_54\lib32-msvc-11.0\boost_python-vc110-mt-gd-1_54.lib
Or whatever your install directory is. As well as any other required files. Once that's done your project should build.
Once you're ready to run it you'll need to copy whatever .dll files are needed into the folder where the executable is built.