The answer to this question (which should not have been downvoted, in my opinion, because it represents a real issue) is to upgrade from the older Microsoft.Web.Optimization package that uses the "Microsoft.Web.Optimization" namespace and making sure you're using their latest, signified by the "System.Web.Optimization" namespace instead.
In the older Microsoft package, Angular would bomb out when handed to JsMinify. Not so anymore in the latest version.
I hadn't realized at first that I was on an older version of that package because the package name changed - hence my spinning my wheels on it for a while.