It sounds like you might have a problem related to a third party package or add-in, possibly not DevExpress related. Here are some things to try:
Running Visual Studio as an administrator.
You can try running devenv /Resetsettings (see here) in a Command Prompt which should fix any corrupted settings
Try running devenv /ResetSkipPkgs (see here) which will avoid loading any problem packages.
Try running devenv /Safemode (see here). If it works in safe mode then the problem is most likely a third party add-ins or package.
You can also try Devenv.exe /log ". This will generate a file called ActivityLog.xml which might give you further clues.
If none of those help then try repairing Visual Studio from the Control Panel.