add the following directives to your .htaccess:
RewriteCond %{HTTP_HOST} (.+)\.co\.uk$
RewriteRule (.*) http://%1.com/en-gb/$1 [R=301,L,QSA]
RewriteCond %{HTTP_HOST} \.com$
RewriteCond %{REQUEST_URI} !^/(en-us|en-gb)/
RewriteRule (.*) /en-us/$1 [R=301,L,QSA]
if you have so many domain TLDs, you maybe want to use RewriteMap to avoid duplicating the first rule for every TLD, RewriteMap will map TLD to Uri string (ex: .co.uk to en-gb),